DNA Synthesis Market Size, Share & Trends Analysis growing at a CAGR of 16.89% from 2025 to 2033
The global DNA synthesis market size was estimated at USD 3.52 billion in 2024 and is projected to reach USD 13.85 billion by 2033, growing at a CAGR of 16.89% from 2025 to 2033. This growth can be attributed to the rising demand for DNA synthesis in various applications, including molecular biology, genetic engineering, clinical diagnostics, and therapeutics.
Key Market Trends & Insights
- The North America DNA synthesis market held the largest share of 39.83% of the global market in 2024.
- The DNA synthesis industry in the U.S. is expected to grow significantly over the forecast period.
- By service type, the oligonucleotide Synthesis segment held the highest market share of 55.49% in 2024.
- Based on application, the research and development segment held the highest market share in 2024.
- By end use, the biopharmaceutical and diagnostics companies segment held the highest market share in 2024.
Market Size & Forecast
- 2024 Market Size: USD 3.52 Billion
- 2033 Projected Market Size: USD 13.85 Billion
- CAGR (2025-2033): 16.89%
- North America: Largest market in 2024
- Asia Pacific: Fastest growing market
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For instance, in May 2025, Ansa Biotechnologies launched a 50 kb DNA synthesis early access program addressing the increasing demand for long, complex DNA constructs in synthetic biology and therapeutics.
Growth in Molecular Biology and Genetic Engineering
Synthetic DNA is vital for precise genetic modifications, gene cloning, and supporting advanced genome editing technologies such as CRISPR-Cas9, which requires custom gene synthesis for designing therapeutic genes, regulatory elements, and gene editing tools. As research in these fields expands, the need for custom-designed DNA sequences has increased significantly, fueling demand for high-quality, reliable synthesis services. For instance, in May 2025, Ribbon Bio GmbH launched MiroSynth DNA molecules, introducing a commercial product designed to meet the growing demand for complex and highly accurate synthetic DNA molecules.
